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Updated: May 25, 2026

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets
Published on: February 22, 2016
Controlled synthesis of 3D multi-compartmental particles with centrifuge-based microdroplet formation from a
Kazuki Maeda1, Hiroaki Onoe, Masahiro Takinoue
1Institute of Industrial Science, The University of Tokyo, Meguro-ku, Tokyo, Japan.
Abstract:
Controlled synthesis of micro multi-compartmental particles using a centrifuge droplet shooting device (CDSD) is reported. Sodium alginate solutions introduced in a multi-barreled capillary form droplets at the capillary orifice under ultrahigh gravity and gelify in a CaCl(2) solution. The size, shape, and compartmentalization of the particles are controlled. Co-encapsulation of Jurkat cells and magnetic colloids into Janus particles is demonstrated. The Janus particles present sensitive reaction toward magnetic fields, while the viability of the encapsulated cells is 91%.

