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A novel flavonoid and furoquinoline alkaloids from Vepris glomerata and their antioxidant activity
Joyce J Kiplimo1, Md Shahidul Islam, Neil A Koorbanally
1School of Chemistry, University of KwaZulu -Natal, Westville Campus, Private Bag X54001, Durban 4000, South Africa.
Abstract:
The dichloromethane extract of the aerial part of the plant Vepris glomerata (Rutaceae) yielded a new flavonoid, which was accorded the trivial name veprisinol (1), together with four known furoquinoline alkaloids: haplopine-3,3'-dimethylallyl ether (2), anhydroevoxine (3), evoxine (4) and skimmianine (5). The structures of the compounds were established by 1D and 2D NMR spectroscopy, as well as HREIMS. Compounds 1 and 2 have strong antioxidant potential, similar to and in some instances better than ascorbic acid and can be used as beneficial additives to antioxidant supplements.
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