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Pattern of malignancy in clinically solitary thyroid nodule.
Mymensingh Medical Journal : MMJ
|February 9, 2012
Summary
Solitary thyroid nodules (STN) carry a higher malignancy risk (15%) than general thyroid swelling. Papillary carcinoma was the most frequent malignancy found in STN patients, particularly in males.
Area of Science:
- Endocrinology
- Oncology
- Surgical Pathology
Background:
- Solitary thyroid nodule (STN) is a prevalent endocrine disorder.
- The risk of malignancy in STN is significantly higher (approximately 15%) compared to generalized thyroid swelling (approximately 3%).
Purpose of the Study:
- To investigate the pattern of malignancy in clinically solitary thyroid nodules.
- To determine the prevalence and types of thyroid cancer within STN cases.
Main Methods:
- A prospective study conducted at Mymensingh Medical College Hospital from November 2008 to October 2009.
- Inclusion of 108 patients diagnosed with solitary thyroid nodules.
- Analysis of clinical presentation, symptoms, and histopathological findings.
Main Results:
- Out of 108 STN cases, 19 (17.59%) were malignant.
- Malignancy was more prevalent in males (25%) than females (14.47%).
- Papillary carcinoma was the most common type (63.16%), followed by follicular (26.31%) and medullary carcinoma (10.53%).
Conclusions:
- Solitary thyroid nodules present a notable risk of malignancy.
- Papillary carcinoma is the predominant histological type of thyroid cancer in STN.
- Early detection and diagnosis are crucial for managing thyroid malignancies.
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