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Histomorphometric study of lumen of human vermiform appendix
M M Rahman1, M Khalil, S Z Sultana
1Department of Anatomy, Community Based Medical College, Mymensingh, Bangladesh.
This study examined the vermiform appendix lumen diameter in Bangladeshi individuals. Females generally exhibited a slightly larger mean luminal diameter compared to males across different age groups.
Area of Science:
- Anatomy
- Histology
- Forensic Medicine
Background:
- The vermiform appendix is a vestigial organ with potential roles in immunity and gut microbiota.
- Understanding its morphometric variations is crucial for anatomical and clinical contexts.
Purpose of the Study:
- To determine the histomorphometry of the vermiform appendix lumen in a Bangladeshi population.
- To investigate potential differences in luminal diameter based on age and sex.
Main Methods:
- A cross-sectional descriptive study involving 100 fresh vermiform appendix specimens.
- Specimens were collected during postmortem examinations at Mymensingh Medical College.
- Luminal diameter measurements were categorized into four age groups (A: up to 20 years, B: 21-35, C: 36-55, D: 56-70 years).
Main Results:
- The mean luminal diameter of the vermiform appendix was slightly greater in females (60.71 μm) than in males (60.11 μm).
- Maximum diameter was observed in Group A females (87.00 μm), and the minimum diameter was found in Group B females (4.70 μm).
Conclusions:
- This study provides baseline histomorphometric data for the Bangladeshi population.
- Age and sex appear to influence vermiform appendix luminal diameter, with females showing a marginally larger mean diameter.
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