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Updated: May 25, 2026

Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics
Published on: July 31, 2021
Synthesis of methoxybenzoflavones and assignments of their NMR data
Doseok Hwang1, Geunhyeong Jo, Jiye Hyun
1Division of Bioscience and Biotechnology, BMIC, Konkuk University, Seoul, 143-701, Korea.
Abstract:
A phytotoxic root exudate from Acroptilon repens was identified as 7,8-benzoflavone, an inhibitor of cytochrome P450 1A2 and activator of cytochrome P450 3A4. The synthetic 5,6-benzoflavone also is a potent phytotoxin. Six 7,8-benzoflavones and eight 5,6-benzoflavones were synthesized in this study. The NMR data for a few of these compounds have been previously reported; however, the NMR data for most of them have not been reported. For reference purposes, the complete NMR data for the 14 benzoflavones are described.
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