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Updated: May 25, 2026

Generation of Induced Pluripotent Stem Cell-Derived iTenocytes via Combined Scleraxis Overexpression and 2D Uniaxial Tension
Published on: March 1, 2024
Stem cells for tendon and ligament tissue engineering and regeneration
N A Siddiqui1, J M L Wong, Wasim S Khan
1Department of Trauma and Orthopaedics, Royal Free Hampstead NHS Trust, London, NW3 2QG, UK.
None:
Tendons and ligaments are frequently injured. Due to their relatively avascular nature, repair is slow and often incomplete. Stem cells offer a new approach to augment healing of native tissues, as well as providing materials to surgically replace injured structures that are beyond repair. Here we discuss the various roles of stem cells in natural repair processes compared to engineered tissues to assist healing or replace tissues.
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