Jove
Visualize
Contact Us

Related Concept Videos

Axial and Appendicular Muscles01:18

Axial and Appendicular Muscles

Skeletal muscles, the key players in our body's movement, can be classified into two groups based on their location and function: axial muscles and appendicular muscles. These classifications reflect the primary roles the muscles play in the body's structure and movement.
Axial Muscles
Axial muscles, situated along the body's midline, are intricately connected to the axial skeleton, which includes the skull, spine, ribs, and sternum. These muscles facilitate facial expressions and play a...
Overview of the Axial Skeleton01:09

Overview of the Axial Skeleton

The skeleton is subdivided into two major divisions—the axial skeleton and the appendicular skeleton. The axial skeleton forms the vertical, central axis of the body. It includes all of the bones of the head, neck, chest, and back. It protects the brain, spinal cord, heart, and lungs. It also serves as the attachment site for muscles that move the head, neck, and back and for muscles that act across the shoulder and hip joints to move their corresponding limbs.
The axial skeleton of the adult...
Articulations of the Vertebral Column01:28

Articulations of the Vertebral Column

In addition to being held together by the intervertebral discs, adjacent vertebrae also articulate with each other at synovial joints formed between the superior and inferior articular processes called zygapophysial joints (facet joints). These are plane joints that provide for only limited motions between the vertebrae. The orientation of the articular processes at these joints varies in different regions of the vertebral column and serves to determine the types of motions available in each...
Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
General Case of Eccentric Axial Loading01:12

General Case of Eccentric Axial Loading

Unsymmetrical bending occurs when the bending moment applied to a structural member does not align with its principal axis. This misalignment leads to complex stress distributions and deflection patterns that differ from symmetrical bending, which are essential for designing structures to withstand different loading conditions.
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical bending,...
Spinal Nerves: Anatomy01:23

Spinal Nerves: Anatomy

Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discontinuation versus continuation of maintenance treatment with tumor necrosis factor inhibitors in patients with rheumatoid arthritis with low disease activity or remission: A randomized double-blind placebo-controlled trial.

Seminars in arthritis and rheumatism·2025
Same author

Naomi Rothfield, MD, MACR: A Giant Gift in a Small Package.

Rheumatic diseases clinics of North America·2023
Same author

A multianalyte assay panel with cell-bound complement activation products demonstrates clinical utility in systemic lupus erythematosus.

Lupus science & medicine·2021
Same author

A Review of Complement Activation in SLE.

Current rheumatology reports·2021
Same author

A Multianalyte Assay Panel With Cell-Bound Complement Activation Products Predicts Transition of Probable Lupus to American College of Rheumatology-Classified Lupus.

ACR open rheumatology·2021
Same author

Evaluation of the Economic Benefit of Earlier Systemic Lupus Erythematosus (SLE) Diagnosis Using a Multivariate Assay Panel (MAP).

ACR open rheumatology·2020
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 25, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Axial (spinal) gout.

Elena Lumezanu1, Rukmini Konatalapalli, Arthur Weinstein

  • 1Washington Hospital Center, Rheumatology, Washington, DC 20010, USA. elena.m.lumezanu@medstar.net

Current Rheumatology Reports
|February 10, 2012
PubMed
Summary
This summary is machine-generated.

Gout can affect the spine, causing serious symptoms like back pain and cord compression. Early detection with CT imaging and prompt treatment, including surgery and uric acid-lowering therapy, can reverse these effects.

More Related Videos

Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

Related Experiment Videos

Last Updated: May 25, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

Area of Science:

  • Rheumatology
  • Orthopedics
  • Radiology

Background:

  • Gout is a metabolic disorder caused by uric acid supersaturation and crystal deposition.
  • While commonly affecting peripheral joints, axial gout (spine involvement) is underrecognized.
  • Spinal gout can lead to severe symptoms including back pain, radiculopathy, and spinal cord compression.

Purpose of the Study:

  • To highlight the prevalence and clinical significance of axial gout.
  • To discuss diagnostic imaging modalities for spinal gout.
  • To outline management strategies for spinal gout and its complications.

Main Methods:

  • Literature review focusing on axial gout diagnosis and management.
  • Emphasis on the role of Computed Tomography (CT) imaging in detecting spinal tophi and erosions.
  • Discussion of surgical intervention and medical management for spinal gout.

Main Results:

  • Axial gout, though less common than appendicular gout, is a significant cause of spinal pathology.
  • Radiological evidence of spinal gout may take years to develop and is best visualized with CT.
  • Surgical decompression and uric acid-lowering therapy can reverse neurological deficits from cord compression.

Conclusions:

  • Axial gout is an important differential diagnosis for spinal conditions, especially in patients with a history of gout.
  • Timely diagnosis and intervention are crucial for favorable outcomes in spinal cord compression due to gout.
  • Long-term effects of urate-lowering therapies on axial gout require further investigation.