Stability of voxel values from cone-beam computed tomography for dental use in evaluating bone mineral content

The objective of this study was to investigate the stability of voxel values from cone-beam CT (CBCT) using a flat panel detector in changing surrounding circumstances mimicking clinical situations.

Seven hydroxyapatite (HA) rods (0, 40, 80, 120, 160, 199, and 239 mg Ca/cm(3) ) were set in a 16 cm diameter water phantom and scanned with CBCT (FineCube) and also with multislice CT (MSCT) used as reference. The voxel values from CBCT were measured by the obtained images with OsiriX software (http://www.osirix-viewer.com), and compared with the CT numbers from MSCT. We examined the correlation between the voxel values and the HA contents, the variance of voxel values, and the influence of changing surrounding circumstances on the voxel values.

The voxel values from CBCT were different from the CT numbers from MSCT, but there was a linear Pearson correlation between the voxel values and the HA contents. The voxel values were greatly influenced when the samples were scanned surrounded in air. However, the voxel values were not affected significantly in the existence of materials simulating oral hard tissues and/or a metal core post.

There was a linear correlation between the voxel values of CBCT and the contents of HA rod samples. Our study indicated that it might be possible to evaluate bone mineral content(BMC) from the voxel values of CBCT for dental implant treatment.