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[Orofacial lymphomas in seropositive patients manifesting the type I human lymphotropic virus (HTLV-I)]
K Kurihara1, H Kohno, K Nakagawa
1Dept. of Pathology, Uwajima City Hospital.
Eleven cases of extranodal orofacial lymphomas (EOFL), consisting of 4 HTLV related and 7 HTLV unrelated EOFLs, have been investigated with regard to their immunohistological and clinical features. The HTLV related EOFLs were found to be of the T-cell phenotype and were associated with a poorer prognosis than the HTLV unrelated EOFLs, most of which were of B-cell origin. The comparatively high incidence of T-cell type in our series was considered to be related to the high percentage of HTLV carriers in our district, an area in which adult T-cell leukemia lymphoma has been found to be endemic.
Eleven cases of extranodal orofacial lymphomas (EOFL), consisting of 4 HTLV related and 7 HTLV unrelated EOFLs, have been investigated with regard to their immunohistological and clinical features. The HTLV related EOFLs were found to be of the T-cell phenotype and were associated with a poorer prognosis than the HTLV unrelated EOFLs, most of which were of B-cell origin. The comparatively high incidence of T-cell type in our series was considered to be related to the high percentage of HTLV carriers in our district, an area in which adult T-cell leukemia lymphoma has been found to be endemic.