Related Experiment Video
Updated: May 25, 2026

MRI and PET in Mouse Models of Myocardial Infarction
Published on: December 19, 2013
[Clinical applications of MIBG SPECT in chronic heart failure]
Gianluigi Savarese1, Teresa Losco, Antonio Parente
1Dipartimento di Medicina Interna, Universita degli Studi, Federico II, Napoli.
Abstract:
Heart failure is characterized by several abnormalities of sympathetic cardiac activity that can be assessed by 123I metaiodobenzylguanidine single photon emission computed tomography (MIBG SPECT). This technique may be useful in the clinical management of heart failure patients. Abnormal MIBG uptake has been demonstrated to be a predictor of death and arrhythmic events in heart failure patients with a prognostic power incremental to that of conventional risk markers; it may also be useful to identify patients at low risk of arrhythmias despite current guideline indications for an implantable cardioverter-defibrillator (ICD) or patients at high risk for arrhythmias not fulfilling ICD indications. This review will focus on the clinical applications of MIBG SPECT in chronic heart failure, on the basis of the most recent evidence.
More Related Videos
08:13In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
12:24Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
Published on: June 20, 2014
Related Concept Videos
Imaging Studies for Cardiovascular System IV: CMRI
Heart Failure Drugs: Inotropic Agents
Heart Failure III: Clinical Manifestations
Mitral Stenosis II: Clinical features and Diagnostic Tests
Heart Failure Drugs: β-Blockers
Cardiomyopathy II: Dilated Cardiomyopathy