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Too many numbers: Microarrays in clinical cancer research

Peter Keating1, Alberto Cambrosio

  • 1Department of History, Université du Québec à Montréal, Case Postale 8888, Succursale Centre-ville, Montréal, Québec, Canada H3C 3P8. keating.peter@uqam.ca

Studies in History and Philosophy of Biological and Biomedical Sciences
|February 14, 2012
PubMed
Abstract

No abstract available in PubMed .

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...