Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence01:22

Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plasma and intrapulmonary pharmacokinetics of ceftibuten and ledaborbactam in healthy male and female adults.

Antimicrobial agents and chemotherapy·2026
Same author

Pharmacokinetic and Pharmacodynamic Principles and Concepts Remain Relevant in the Era of Artificial Intelligence and Machine Learning.

Pharmacotherapy·2026
Same author

Pivmecillinam for Treatment of Uncomplicated Urinary Tract Infection: New Efficacy Analysis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2025
Same author

Plasma and intrapulmonary pharmacokinetics of cefepime and taniborbactam in healthy adult participants.

Antimicrobial agents and chemotherapy·2025
Same author

Intrapulmonary pharmacokinetics of SPR719 following oral administration of SPR720 to healthy volunteers.

Antimicrobial agents and chemotherapy·2024
Same author

Lessons Are Still Being Learned about Intrapulmonary Antibiotic Concentrations.

American journal of respiratory and critical care medicine·2024
Same journal

Understanding the Clone-Censor-Weight Method in Observational Studies of Antibiotic Duration.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Treatment of Progressive Multifocal Leukoencephalopathy with Third-Party Allogeneic BK Virus T Cells.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Protection Against Recurrent Typhoid Fever Conferred by a Prior Episode: Evidence from a Large Cohort Study in Dhaka, Bangladesh.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Pre-treatment Gut Microbiome Diversity and Function Linked to Cytotoxic and Natural Killer Cell Immune Responses after N-803 Treatment in People with HIV.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Reconsidering ambiguous language in infectious disease consult recommendations.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Antibiotic Treatment Duration for Uncomplicated Monomicrobial Enterococcal Bloodstream Infection: A Multicenter Target Trial Emulation.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
See all related articles

Related Experiment Videos

Vancomycin for surgical prophylaxis?

Tonya Crawford1, Keith A Rodvold, Joseph S Solomkin

  • 1Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, IL 60612-7230, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|February 14, 2012
PubMed
Summary
This summary is machine-generated.

Vancomycin is generally not recommended for routine surgical prophylaxis due to rising methicillin-resistant Staphylococcus aureus (MRSA) rates. It may be considered in specific high-MRSA situations as part of a comprehensive prevention strategy for surgical site infections (SSIs).

Related Experiment Videos

Area of Science:

  • Infectious Diseases
  • Surgical Infection Prevention
  • Antimicrobial Stewardship

Background:

  • Increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) necessitates reevaluating antibiotic prophylaxis protocols.
  • Previous studies suggest cephalosporins are effective, but are outdated and do not reflect current MRSA rates.
  • Current MRSA prevalence impacts the efficacy and cost-effectiveness of vancomycin for surgical site infection (SSI) prevention.

Purpose of the Study:

  • To review the current evidence on vancomycin's role in surgical prophylaxis.
  • To assess the effectiveness of vancomycin in high-MRSA prevalence settings.
  • To determine optimal strategies for preventing SSIs caused by resistant pathogens.

Main Methods:

  • Systematic reviews of randomized controlled trials.
  • Time-series analyses in high-MRSA prevalence institutions.
  • Decision analysis models to estimate MRSA prevalence thresholds.
  • Review of combination therapy and resistance emergence.

Main Results:

  • Existing evidence on cephalosporins vs. vancomycin is largely based on older data.
  • Recent analyses evaluate vancomycin effectiveness in contemporary high-MRSA environments.
  • Decision models identify specific MRSA prevalence rates where vancomycin might be beneficial.
  • Emergence of resistant pathogens is a concern with vancomycin prophylaxis.

Conclusions:

  • Vancomycin is not recommended for routine surgical prophylaxis.
  • Consider vancomycin as part of a bundled approach for MRSA SSI prevention in select cases.
  • Antimicrobial stewardship is crucial for managing resistance and optimizing SSI prevention strategies.