Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pancreatic exocrine insufficiency.

EClinicalMedicine·2026
Same author

International Multidisciplinary Consensus Report on Definitions, Diagnostic Criteria, and Management of Fatty Pancreas: A Joint Statement Endorsed by EPC, APA, EASD, EASL, ESGAR, ESGE, ESP, ESPCG, ESPEN, ESPGHAN, IAP, JPS, KPBA, LAPSG, and UEG.

United European gastroenterology journal·2026
Same author

Strain ratio vs strain histogram for the elastographic evaluation of non-calcific chronic pancreatitis (CP) ‒ A prospective, single-center, comparative study.

Revista espanola de enfermedades digestivas·2025
Same author

Indoor radon concentration and risk and severity of inflammatory bowel diseases: a case-control study.

Therapeutic advances in gastroenterology·2025
Same author

Cystic pancreatic lesions: when to watch and when to act?

Revista espanola de enfermedades digestivas·2025
Same author

In-Vitro Comparison of Physical Characteristics, Enzyme Content, and Release Kinetics of Pancreatic Enzyme Preparations Available in Europe and Canada.

Drugs in R&D·2025
Same journal

ENDOSCOPIC REMOVAL OF BONE FOREIGN BODY EMBEDDED IN THE COLON.

Gastroenterologia y hepatologia·2026
Same journal

An uncommon endoscopic finding: esophageal intramural pseudodiverticulosis.

Gastroenterologia y hepatologia·2026
Same journal

Anemia and Hypoalbuminemia are Associated with Hepatic Encephalopathy and Mortality after Portal Hypertension-Related Bleeding.

Gastroenterologia y hepatologia·2026
Same journal

Optimization of a mobile application for the management of hepatitis D based on patient experience: an observational study in a hepatology cohort.

Gastroenterologia y hepatologia·2026
Same journal

Assessment of Training in Pancreatology and Biliary Diseases During Gastroenterology Residency: A National Survey by AEG-AESPANC.

Gastroenterologia y hepatologia·2026
Same journal

HEPATOCELLULAR CARCINOMA SURVEILLANCE: A PRACTICAL GUIDEBASED ON CURRENT EVIDENCE.

Gastroenterologia y hepatologia·2026
See all related articles

Related Experiment Video

Updated: May 25, 2026

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
06:44

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

Published on: February 28, 2021

[Chronic pancreatitis].

J Enrique Domínguez-Muñoz1

  • 1Servicio de Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, España. enriquedominguezmunoz@hotmail.com

Gastroenterologia Y Hepatologia
|February 15, 2012
PubMed
Summary
This summary is machine-generated.

New research highlights pregabalin

More Related Videos

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation
06:28

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

Related Experiment Videos

Last Updated: May 25, 2026

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
06:44

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

Published on: February 28, 2021

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation
06:28

An Obstructive Chronic Pancreatitis Model Established Through Electrocoagulation

Published on: October 31, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

Area of Science:

  • Gastroenterology and Hepatology
  • Medical Imaging
  • Clinical Pharmacology

Context:

  • Digestive Disease Week meeting presented key findings on chronic pancreatitis.
  • Endoscopic ultrasound (EUS) is the standard for diagnosing chronic pancreatitis.
  • Early-stage diagnosis and specific criteria remain areas of active research.

Purpose:

  • To summarize recent clinical advancements in chronic pancreatitis diagnosis and management.
  • To evaluate the utility of Endoscopic Ultrasound (EUS) and its classifications.
  • To present new therapeutic options for chronic pancreatitis pain.

Summary:

  • Endoscopic ultrasound (EUS) is crucial for diagnosing chronic pancreatitis, but its effectiveness in early stages and with fewer criteria is debated.
  • New evidence supports EUS for autoimmune pancreatitis diagnosis.
  • A randomized trial demonstrated pregabalin's efficacy in managing chronic pancreatitis pain.

Impact:

  • Findings may refine diagnostic criteria for chronic pancreatitis, particularly in early or ambiguous cases.
  • EUS utility is confirmed for autoimmune pancreatitis.
  • Pregabalin emerges as a potential treatment for pain management in chronic pancreatitis.