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Updated: May 25, 2026

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
Published on: February 28, 2021
[Chronic pancreatitis]
1Servicio de Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, España. enriquedominguezmunoz@hotmail.com
Abstract:
The present article summarizes some of the most important results with potential clinical impact on the diagnosis and management of chronic pancreatitis presented at the last meeting of Digestive Disease Week. Endoscopic ultrasound (EUS) is currently the method of choice for the diagnosis of chronic pancreatitis in clinical practice. However, some new studies suggest that the Rosemont classification is not useful for diagnosis of this disease in the early stages, whereas others show that, in patients with abdominal pain, chronic pancreatitis cannot be excluded even when there are less than three EUS criteria of the disease. In contrast, new studies support the usefulness of endoscopic ultrasound for the diagnosis of autoimmune pancreatitis in the presence of pancreatic ductitis. From the therapeutic point of view, a notable contribution at the congress was a new randomized placebo-controlled clinical trial showing the efficacy of pregabalin for the treatment of pain in chronic pancreatitis.
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Chronic Pancreatitis I: Introduction
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Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Pathophysiology
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Assessment:
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis I: Introduction

