Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Laser in situ keratomileusis.

I G Pallikaris1, M E Papatzanaki, E Z Stathi

  • 1Department of Ophthalmology, School of Health Sciences, University of Crete, Greece.

Lasers in Surgery and Medicine
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65.

Gene therapy·2024
Same author

Lateral gain is impaired in macular degeneration and can be targeted to restore vision in mice.

Nature communications·2022
Same author

Atomic force microscopy for the characterisation of pinning effects of seawater micro-droplets in n-decane on a calcite surface.

Journal of colloid and interface science·2021
Same author

Outcome of refractory to conventional and/or biologic treatment adult Still's disease following canakinumab treatment: Countrywide data in 50 patients.

Seminars in arthritis and rheumatism·2020
Same author

Relationship between wetting and capillary pressure in a crude oil/brine/rock system: From nano-scale to core-scale.

Journal of colloid and interface science·2019
Same author

Model-free classification of X-ray scattering signals applied to image segmentation.

Journal of applied crystallography·2018

This study explores a novel laser refractive surgery in rabbits, creating corneal flaps and stromal ablations. Early haze and flap edge opacification resolved over 4 weeks, suggesting potential for stable corneal changes.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Laser Technology

Background:

  • Laser refractive surgery aims to correct vision by reshaping the cornea.
  • Developing new surgical techniques is crucial for improving patient outcomes and safety.

Purpose of the Study:

  • To evaluate a novel laser refractive procedure in a rabbit model.
  • To assess the immediate and short-term effects of the procedure on corneal tissue.

Main Methods:

  • Central corneal flaps were created using a modified microkeratome.
  • An ArF excimer laser performed 3-mm circular ablations on the stromal bed.
  • Scanning electron microscopy and light microscopy analyzed corneal healing post-surgery.

Main Results:

Related Experiment Videos

  • Immediate examination revealed dissected and ablated areas.
  • Postoperative haze in stromal areas decreased over 4 weeks but remained visible.
  • Hemicircular opacification at flap edges and thickened epithelium at margins were observed.
  • Increased keratocytes were noted at the flap-stroma interface.

Conclusions:

  • The laser refractive procedure in rabbits showed initial corneal haze and opacification.
  • Corneal healing involved epithelial changes and keratocyte proliferation.
  • Preservation of anterior corneal layers may lead to stable refractive changes.