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Updated: May 24, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Current management and novel agents for malignant melanoma
Byung Lee1, Nikhil Mukhi, Delong Liu
1Division of Hematology and Oncology, New York Medical College and Westchester Medical Center, Valhalla, New York 10595, USA.
Abstract:
Advanced malignant melanoma remains a challenging cancer. Over the past year, there have been 3 agents approved for treatment of melanoma by Food and Drug Administration. These include pegylated interferon alpha-2b for stage III melanoma, vemurafenib for unresectable or metastatic melanoma with BRAF V600E mutation, and ipilimumab for treatment of unresectable or metastatic melanoma. This review will also update on the development of novel agents, including tyrosine kinase inhibitors and adoptive cellular therapy.
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