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Updated: May 24, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Infection prevention strategy for antimicrobial-resistant organisms]
1Dept. of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, Japan.
Antimicrobial resistance poses a significant threat, especially to immunocompromised cancer patients. Infection prevention strategies like standard and contact precautions, environmental cleanliness, and antimicrobial stewardship are crucial for combating resistant organisms in hospitals.
Area of Science:
- Infection Prevention and Control
- Oncology
- Microbiology
Background:
- Antimicrobial-resistant organisms (AROs) present a major challenge in infection prevention.
- Cancer patients are particularly vulnerable due to frequent immunocompromise, increasing their risk of nosocomial infections.
- Hospitals are potential reservoirs for AROs, necessitating robust infection control measures.
Purpose of the Study:
- To highlight the critical issue of antimicrobial resistance in oncology settings.
- To outline key infection prevention strategies against AROs.
- To emphasize the importance of environmental hygiene and antimicrobial stewardship.
Main Methods:
- Review of standard and contact precautions for infection prevention.
- Emphasis on hospital environmental cleanliness to reduce resistant bacteria.
- Discussion of antimicrobial stewardship programs.
Main Results:
- Standard and contact precautions are major techniques for preventing nosocomial infections caused by AROs.
- Hospital environmental cleanliness is vital for reducing the presence of resistant bacteria.
- Antimicrobial stewardship is essential for mitigating the emergence of AROs.
Conclusions:
- Comprehensive infection prevention strategies are necessary to combat antimicrobial resistance in oncology.
- Maintaining a clean hospital environment and implementing antimicrobial stewardship are key to reducing AROs.
- Protecting immunocompromised cancer patients requires a multi-faceted approach to infection control.
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