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Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes
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Transition metal catalysis and nucleophilic fluorination

Charlotte Hollingworth1, Véronique Gouverneur

  • 1Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, OX1 3TA, Oxford, UK.

Chemical Communications (Cambridge, England)
|February 16, 2012
PubMed
Summary

This review highlights advances in transition metal-catalyzed nucleophilic fluorination for synthesizing valuable fluorinated compounds and pharmaceuticals. New fluoride reagents are enabling broader applications, including in Positron Emission Tomography (PET) imaging.

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