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Updated: Jan 26, 2026

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
[Is it efficacy for the treatment of idiopathic optic neuritis with glucocorticosteroid]
Xiu-lan Zhang1, Wei Wang, Shi-hui Wei
1Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou 510060, China. xiulan_z@yahoo.com
Abstract:
Glucocorticosteroid (steroid) therapy is the major treatment for some important neuro-ophthalmological diseases. However, its efficacy, safety and abuse raise great controversy and debate for a long time, many clinical problems also remain to be solved. This paper discusses the issues relevant to the treatment of idiopathic optic neuritis by steroid and strongly advocate carrying out an evidence-based multicenter randomized clinical trial in China. It is suggested to establish a standard guideline or consensus for the treatment of neuro-ophthalmological diseases with steroid.
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