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Lung carcinoma: its profile and changing trends
Saad Siddiqui1, Mohammed Usman Ali, Mahrukh Ayesha Ali
1The Aga Khan University Medical College, Karachi, Pakistan. saadsiddiqui.5@gmail.com
Journal of Ayub Medical College, Abbottabad : JAMC
|February 18, 2012
Summary
Squamous Cell Carcinoma is the most common lung cancer type, with its prevalence significantly increasing in both males and females. Small Cell Carcinoma also saw a rise, particularly in males.
Area of Science:
- Oncology
- Pulmonology
- Pathology
Background:
- Lung carcinoma is a major global health burden, causing significant morbidity and mortality.
- An estimated 1.3 million new cases occur annually worldwide.
- Understanding histological type prevalence and trends is crucial for public health strategies.
Purpose of the Study:
- To determine the prevalence of different lung carcinoma histological types.
- To analyze temporal trends in lung carcinoma histology.
- To provide regional data on lung cancer epidemiology.
Main Methods:
- Retrospective analysis of 330 lung carcinoma cases from 2003-2008.
- Inclusion of cases from Khyber Pakhtunkhwa and Federally Administered Tribal Area (FATA).
- Exclusion of non-lung carcinoma malignancies.
Main Results:
- Squamous Cell Carcinoma (SCC) was the most prevalent type (42.7%).
- SCC prevalence increased from 32% to 57.9% over the study period.
- Small Cell Carcinoma (SCLC) prevalence increased from 12% to 17.1%, notably in males.
Conclusions:
- SCC is the predominant lung carcinoma histological type in the studied region.
- A statistically significant increase in SCC prevalence was observed in both sexes.
- A significant increase in SCLC prevalence was noted in males.
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