Related Experiment Video
Updated: May 24, 2026

Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
Sensorial saturation for infants' pain
Carlo Valerio Bellieni1, Monica Tei, Francesca Coccina
1Department of Pediatrics, Obstetrics and Reproduction Medicine, University of Siena, Siena, Italy.
Insights
Sensorial saturation (SS) effectively relieves neonatal pain during procedures. This multisensorial stimulation is more effective than oral solutions alone, promoting nurse-infant interaction.
Area of Science:
- Neonatal care
- Pain management
Background:
- Sensorial saturation (SS) is a multisensorial stimulation involving tactile, gustative, auditory, and visual stimuli.
- The procedure includes facial massage, gentle vocalization, and administering a sweet solution to the infant's tongue.
Purpose of the Study:
- To systematically review the effectiveness of sensorial saturation (SS) in managing neonatal pain.
Main Methods:
- A systematic Medline search was conducted for human neonatal studies on SS.
- The search focused on articles published within the last 10 years, up to January 2012.
Main Results:
- Eight articles utilized complete SS, and two used incomplete SS.
- Complete SS effectively relieved newborn pain, outperforming oral solutions alone.
- Partial SS showed some effectiveness, but less than complete SS; stimuli without sweet solution were ineffective.
Conclusions:
- Sensorial saturation (SS) is a safe and effective analgesic for newborns undergoing minor painful procedures like blood draws.
- SS is superior to oral sugar alone for pain relief.
- SS enhances nurse-infant interaction and is a valuable tool in neonatal intensive care units.
Introduction:
Sensorial saturation (SS) is a multisensorial stimulation consisting of delicate tactile, gustative, auditory and visual stimuli. This procedure consists of simultaneously: attracting the infant's attention by massaging the infant's face; speaking to the infant gently, but firmly, and instilling a sweet solution on the infant's tongue.
Methods:
We performed a systematic Medline search of for articles focusing on human neonatal studies related to SS. The search was performed within the last 10 years and was current as of January 2012.
Results:
We retrieved 8 articles that used a complete form of SS and 2 articles with an incomplete SS. Data show that the use of SS is effective in relieving newborns' pain. Oral solution alone are less effective than SS, but the stimuli without oral sweet solution are ineffective. the partial forms of SS have some effectiveness, but minor than the complete SS. Only one article showed lack of SS as analgesic method, after endotracheal suctioning.
Conclusions:
SS can be used for all newborns undergoing blood samples or other minor painful procedures. It is more effective than oral sugar alone. SS also promotes interaction between nurse and infant and is a simple effective form of analgesia for the neonatal intensive care unit.
Related Concept Videos
Pain
Somatosensation
Sensation
Absolute thresholds can quantify the sensitivity of sensory...
Sensory Perception: Organization of the Somatosensory System
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Sensory Functions of the Skin
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Thermosensation

