The psychosocial impact of haematopoietic SCT on sibling donors

B Pillay1, S J Lee, L Katona

  • 1School of Psychology and Psychiatry, Monash University, Clayton, Victoria, Australia.

Bone Marrow Transplantation
|February 21, 2012
PubMed

Insights

Sibling donors experience varied emotions during peripheral blood stem cell (PBSC) donation. Understanding these psychosocial impacts is crucial for providing adequate support to stem cell donors.

Area of Science:

  • Hematology
  • Oncology
  • Psychology

Background:

  • Stem cell transplantation (SCT) has significant physical and psychosocial effects on cancer patients and their families.
  • The psychosocial experiences of sibling donors undergoing invasive procedures are less understood.

Purpose of the Study:

  • To explore the psychosocial impact of peripheral blood stem cell (PBSC) donation on sibling donors.
  • To understand donor experiences during preparation, donation, and post-donation phases.

Main Methods:

  • Interviews and questionnaires were used to collect data from 22 sibling donors (aged mean 53.1 years) who donated between 2007 and 2010.
  • Data collection involved face-to-face or telephone interviews.

Main Results:

  • Donors reported a wide spectrum of positive and negative emotions throughout the donation process.
  • Psychosocial impact was influenced by logistical factors, family dynamics, preparation, emotional support, and health outcome uncertainty.

Conclusions:

  • Routine psychosocial support for both stem cell donors and recipients is essential.
  • Addressing the multifaceted psychosocial needs of sibling donors can improve their overall experience.

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Relationship with Other Adult Family Members and Siblings01:29

Relationship with Other Adult Family Members and Siblings

Other adult family members and siblings play a crucial role in shaping children’s social and emotional development. While parents or primary caregivers are often the central figures in early attachment and socialization, other adults in a child’s life, such as grandparents, aunts, and uncles, can significantly influence developmental outcomes. These influences depend on each adult’s personality and may help compensate when a primary caregiver is emotionally distant or inconsistent. For...
Regulation of Hematopoietic Stem Cells01:01

Regulation of Hematopoietic Stem Cells

All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...