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Related Experiment Video

Updated: May 24, 2026

Evisceration of Mouse Vitreous and Retina for Proteomic Analyses

Evisceration of Mouse Vitreous and Retina for Proteomic Analyses

Published on: April 3, 2011

Evisceration in the modern age.

Laura T Phan¹, Thomas N Hwang, Timothy J McCulley

¹Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore.

Middle East African Journal of Ophthalmology

|February 21, 2012

Summary

Evisceration, an eye surgery, is safe and effective for blind painful eyes and trauma, with minimal risk of sympathetic ophthalmic (SO) complications. Innovations enhance its cosmetic outcomes, increasing its popularity.

Keywords:

Endophthalmitis Enucleation Evisceration Intraocular Tumors

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Area of Science:

Ophthalmology
Ophthalmic Surgery

Background:

Evisceration removes eye contents, potentially exposing uveal antigens, raising historical concerns for sympathetic ophthalmic (SO) complications.
Sympathetic ophthalmic (SO) is a rare complication following evisceration, despite historical concerns.

Purpose of the Study:

To review the clinical applications and safety of evisceration.
To assess the risk of sympathetic ophthalmic (SO) following evisceration.
To discuss technical innovations and the renewed popularity of evisceration.

Main Methods:

Literature review of evisceration and sympathetic ophthalmic (SO) occurrence.
Analysis of clinical applications, contraindications, and technical advancements in evisceration.

Main Results:

Sympathetic ophthalmic (SO) is exceedingly rare after evisceration.
Evisceration is indicated for ocular trauma and blind painful eyes, contraindicated in intraocular malignancy, and suitable for end-stage endophthalmitis.
Scleral modification innovations address previous limitations in orbital implant size.

Conclusions:

Evisceration is a safe and effective procedure with excellent cosmetic results.
The risk of sympathetic ophthalmic (SO) is minimal, making evisceration a viable alternative to enucleation in select cases.
Technical advancements are contributing to the increasing popularity of evisceration.