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Updated: May 24, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Anterior segment tomography with the cirrus optical coherence tomography
Eduardo B Rodrigues1, Margara Johanson, Fernando M Penha
1Department of Ophthalmology, Vision Institute, UNIFESP, Sao Paulo, Brazil.
Optical coherence tomography (OCT) is a key imaging tool for diagnosing eye conditions. This review highlights OCT
Area of Science:
- Ophthalmology
- Biomedical Optics
- Medical Imaging
Background:
- Optical coherence tomography (OCT) is a non-invasive imaging technique utilizing light waves to capture cross-sectional images of biological tissues.
- OCT has emerged as a crucial technology in ophthalmology for the diagnosis and monitoring of macular diseases.
- Advancements in OCT technology have expanded its utility to evaluate ocular structures beyond the macula.
Purpose of the Study:
- To provide a comprehensive overview of the clinical applications of OCT in evaluating anterior segment structures of the eye.
- To detail the diagnostic capabilities of OCT for various ocular conditions affecting the cornea, iris, ciliary body, and anterior chamber angle.
Main Methods:
- Review of existing literature and clinical practices involving OCT for anterior segment imaging.
- Analysis of OCT's role in assessing the integrity and morphology of the cornea, iris, ciliary body, and optic nerve.
- Discussion of OCT's application in diagnosing conditions related to the anterior chamber angle and corneal topography.
Main Results:
- OCT enables detailed assessment of corneal layers, crucial for diagnosing conditions like keratoconus.
- OCT provides high-resolution imaging of the iris and ciliary body, aiding in the diagnosis of tumors and inflammatory conditions.
- OCT is effective in evaluating the anterior chamber angle for glaucoma screening and monitoring.
Conclusions:
- Optical coherence tomography is a versatile and indispensable tool for comprehensive ocular diagnostics.
- OCT's application extends from posterior segment pathologies to detailed anterior segment evaluation, enhancing clinical decision-making.
- The continued development of OCT promises further advancements in the early detection and management of eye diseases.
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