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Related Experiment Videos

Cytomegalovirus isolation from a human inner ear.

L E Davis, C G James, F Fiber

    The Annals of Otology, Rhinology, and Laryngology
    |May 1, 1979
    PubMed
    Summary

    Congenital Cytomegalovirus (CMV) infection can cause infant hearing loss. This study found CMV in the inner ear fluid of an infant with congenital CMV syndrome, confirming viral labyrinth infection.

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    THE MAMMALIAN CELL-VIRUS RELATIONSHIP : V. SUSCEPTIBILITY AND RESISTANCE OF CELLS IN VITRO TO INFECTION BY COXSACKIE A9 VIRUS.

    The Journal of experimental medicine·2009

    Area of Science:

    • Virology
    • Otolaryngology
    • Pediatrics

    Background:

    • Congenital Cytomegalovirus (CMV) infection is a known risk factor for infant hearing loss.
    • Previous evidence linking CMV to congenital deafness was primarily based on clinical and pathological data.

    Observation:

    • A case study of an infant diagnosed with congenital CMV syndrome.

    Findings:

    • Cytomegalovirus (CMV) was successfully isolated from the perilymph of the inner ear.
    • This provides direct virological evidence of CMV infecting the inner ear structures.

    Implications:

    • Confirms that CMV can directly infect the inner ear (labyrinth) in congenital infections.
    • Highlights the potential for direct viral damage to auditory structures in congenital CMV.
    • Supports the need for further research into the mechanisms of CMV-induced hearing loss.

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