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Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy
Published on: January 7, 2019
A prototype stimulator system for noninvasive Low Intensity Focused Ultrasound delivery
Amit P Mulgaonkar1, Rahul S Singh, Meghedi Babakhanian
1Center for Advanced Surgical and Interventional Technology (CASIT), Los Angeles, CA 90095, USA. amitm@ucla.edu
Studies in Health Technology and Informatics
|February 24, 2012
Abstract:
A prototype Low Intensity Focused Ultrasound (LIFU) stimulator system was developed to evaluate non-invasive neuromodulation in a large animal model. We conducted a feasibility study on a Göttingen minipig, demonstrating reversible, targeted transcranial neuromodulation. The hypothalamus of the minipig was repeatedly stimulated with LIFU which evoked temporally correlated increases in both heart rate and blood pressure.

