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Related Concept Videos

Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
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Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...

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Related Experiment Video

Updated: May 24, 2026

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication
09:52

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication

Published on: September 20, 2016

Inflammatory pseudotumor: the great mimicker.

Madhavi Patnana1, Alexander B Sevrukov, Khaled M Elsayes

  • 1Department of Diagnostic Radiology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Mail Unit 1473, Houston, TX 77030, USA. madhavi.patnana@mdanderson.org

AJR. American Journal of Roentgenology
|February 24, 2012
PubMed
Summary
This summary is machine-generated.

Inflammatory pseudotumor is a rare benign condition that can mimic cancer across many organs. Familiarity with its imaging features aids radiologists in diagnosis, potentially avoiding unnecessary surgeries.

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Area of Science:

  • Pathology
  • Radiology
  • Oncology

Background:

  • Inflammatory pseudotumor (IPT) is a rare, benign lesion.
  • IPT can occur in virtually any organ system.
  • It often mimics malignant neoplasms clinically and radiologically.

Purpose of the Study:

  • To review the pathophysiology of IPT.
  • To outline the differential diagnosis for IPT.
  • To describe imaging features and management strategies for IPT.

Main Methods:

  • Literature review of IPT cases.
  • Analysis of pathophysiologic findings.
  • Correlation of imaging features with histopathology.

Main Results:

  • IPT presents with diverse histopathologic findings.
  • Imaging characteristics vary depending on location.
  • Key imaging features aid in differentiating IPT from malignancy.

Conclusions:

  • IPT is a rare, benign entity mimicking malignancy.
  • Found across nearly all organ systems.
  • Radiologists' awareness can prevent misdiagnosis and unnecessary surgery.