Related Experiment Video

Updated: Oct 13, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

[Intravitally undetected tuberculosis and non-registered foci od tuberculous infection]

V F Didenko, A A Ermilov, Z S Baranova

    Problemy Tuberkuleza
    |January 1, 1990
    PubMed

    Insights

    A study of 11,042 postmortem certificates found active pulmonary tuberculosis in 1.55% of cases. Most individuals with tuberculosis were undiagnosed, highlighting a critical gap in public health surveillance and disease control.

    Area of Science:

    • Forensic Pathology
    • Public Health
    • Epidemiology

    Background:

    • Active pulmonary tuberculosis remains a significant public health concern.
    • Undiagnosed tuberculosis cases contribute to disease transmission and mortality.
    • Forensic postmortem examinations offer insights into disease prevalence.

    Purpose of the Study:

    • To determine the prevalence of active pulmonary tuberculosis in postmortem examination records.
    • To assess the proportion of tuberculosis cases that were previously undiagnosed.
    • To evaluate the role of forensic pathology in identifying tuberculosis.

    Main Methods:

    • Retrospective analysis of 11,042 postmortem certificates over a 4-year period.
    • Review of forensic medical examination archives.
    • Categorization of tuberculosis as a cause of death or concurrent condition.

    Main Results:

    • Active pulmonary tuberculosis was identified in 1.55% of the reviewed cases.
    • A significant majority (66.35%) of these cases were not registered with a dispensary.
    • Tuberculosis was the primary cause of death in 72.7% of identified cases.

    Conclusions:

    • Forensic postmortem data reveals a substantial burden of undiagnosed active pulmonary tuberculosis.
    • Improved dispensary registration and early detection are crucial for tuberculosis control.
    • Enhanced collaboration between forensic experts, phthisiologists, and epidemiologists can improve the epidemiological situation.

    More Related Videos

    Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection09:54

    Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

    Published on: February 16, 2020

    Intravital Imaging of Attenuated Auxotrophic Mycobacterium tuberculosis in Murine Lung during Early Intravascular Infection14:26

    Intravital Imaging of Attenuated Auxotrophic Mycobacterium tuberculosis in Murine Lung during Early Intravascular Infection

    Published on: June 30, 2026

    Related Concept Videos

    Pulmonary Tuberculosis I01:29

    Pulmonary Tuberculosis I

    Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
    Causative Organism
    The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
    Mode of...
    Pulmonary Tuberculosis II01:28

    Pulmonary Tuberculosis II

    Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
    Here is a detailed explanation of its pathophysiology:
    Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
    Pulmonary Tuberculosis III01:31

    Pulmonary Tuberculosis III

    Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
    The first classification is based on the development of the disease, and it includes the following categories:
    Pulmonary Tuberculosis IV01:26

    Pulmonary Tuberculosis IV

    Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
    Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
    Pulmonary Tuberculosis V01:28

    Pulmonary Tuberculosis V

    Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
    Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
    Tuberculosis01:23

    Tuberculosis

    Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...