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Updated: Oct 24, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
[The microcirculatory bed within the brain stem in the acute period of severe craniocerebral trauma]
Abstract:
The authors studied changes of the intrastem microcirculatory channel in 72 patients who died in various terms of the acute period of severe craniocerebral trauma. According to the mechanism of the injury, an acceleration trauma had occurred in all cases. The microcirculatory channel was studied by filling it with an indicator mass (gelatin + india ink) and subsequent measurement of the length of the capillary network per 1 mm3 in various parts of the brain stem by the method suggested by S. M. Blinkov and G. D. Moiseev. As a control, a similar study was conducted in 20 individuals who died from extracranial injuries. Significant changes were revealed in the microcirculatory channel of the brain stem in the early period of craniocerebral trauma, and their periodization was established.
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