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Related Experiment Video

Updated: May 24, 2026

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
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Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles

Published on: November 14, 2018

Water-soluble nanodiamond.

Oleksandr Kuznetsov1, Yanqiu Sun, Ryan Thaner

  • 1Department of Physics, Rice University, Houston, Texas 77005, United States.

Langmuir : the ACS Journal of Surfaces and Colloids
|February 25, 2012
PubMed
Summary

Researchers created a nanodiamond salt that can be functionalized with organic groups. This process enhances nanodiamond solubility in water, paving the way for new applications.

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Area of Science:

  • Materials Science
  • Organic Chemistry
  • Nanotechnology

Background:

  • Annealed nanodiamonds possess reactive graphenic edges.
  • Functionalization of nanomaterials is key to tailoring their properties.

Purpose of the Study:

  • To develop a method for functionalizing nanodiamonds.
  • To enhance the water solubility of nanodiamonds.

Main Methods:

  • Reduction of nanodiamond edges using sodium in liquid ammonia to form a nanodiamond salt.
  • Reaction of the nanodiamond salt with alkyl or aryl halides to generate free radicals.
  • Functionalization via radical addition to aromatic rings.
  • Sulfonation and conversion to sodium salts.
  • Preparation of carboxylate-functionalized nanodiamonds.

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A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
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A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

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Formulation and Characterization of Bioactive Agent Containing Nanodisks
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Published on: November 14, 2018

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
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A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

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Main Results:

  • Nanodiamonds were successfully functionalized with phenyl radicals and carboxylic acid groups.
  • Phenyl-functionalized nanodiamond sodium salt showed a water solubility of 248 mg/L.
  • Carboxylate-functionalized nanodiamond sodium salt exhibited a water solubility of 160 mg/L.

Conclusions:

  • A novel route to functionalize nanodiamonds was established.
  • The developed methods significantly improve nanodiamond water solubility.
  • This work opens possibilities for nanodiamonds in aqueous applications.