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RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction

José Almeida Cruz1, Marc-Frédérick Blanchet, Michal Boniecki

  • 1Architecture et Réactivité de l'ARN, Université de Strasbourg, IBMC-CNRS, F-67084 Strasbourg, France.

RNA (New York, N.Y.)
|February 25, 2012
PubMed
Abstract

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RNA Structure01:23

RNA Structure

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RNA Structure

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Nucleic Acid Structure

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DNA Structure
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RNA Stability

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Ribozymes

The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
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