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Updated: May 24, 2026

In Situ Hybridization Techniques for Paraffin-Embedded Adult Coral Samples
Published on: August 31, 2018
Tetrahydrofuran cembranoids from the cultured soft coral Lobophytum crassum
Nai-Lun Lee1,2, Jui-Hsin Su1,2
1National Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan.
Abstract:
Three new cembranoids, culobophylins A-C (1-3), along with two known compounds (4 and 5) were isolated from the cultured soft coral Lobophytum crassum. The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues. Among these metabolites, 2 is rarely found in cembranoids possessing an isopropyl moiety with an epoxide group. Compound 1 exhibited significant cytotoxic activity against HL60 and DLD-1 cancer cell lines.
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