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A surgically treated case of chronic necrotizing aspergillosis with pleural invasion

Kyung-Hak Lee1, Se Min Ryu, Sung-Min Park

  • 1Department of Thoracic and Cardiovascular Surgery, Kangwon National University Hospital, Kangwon National University School of Medicine, Korea.

The Korean Journal of Thoracic and Cardiovascular Surgery
|February 25, 2012
PubMed

Insights

Chronic necrotizing pulmonary aspergillosis is rare, but a successful Korean case highlights the need for combined medical and surgical treatment. This approach, including antifungal drugs and surgery, offers hope for managing this severe fungal infection.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Thoracic Surgery

Background:

  • Aspergillus is a common fungus with variable pathogenicity.
  • Chronic necrotizing aspergillosis (CNA) is an uncommon and severe manifestation of Aspergillus infection.
  • Few CNA cases have been documented in Korea, making this report significant.

Observation:

  • A 52-year-old male presented with chronic necrotizing pulmonary aspergillosis.
  • The case involved pleural aspergillosis, complicating the pulmonary infection.
  • The patient exhibited a successful response to a comprehensive treatment strategy.

Findings:

  • Surgical intervention included lobectomy, decortication, and myoplasty.
  • Medical management involved amphotericin B followed by voriconazole.
  • Local treatment with pleural irrigation using amphotericin B was also administered.

Implications:

  • A multi-dimensional treatment approach is crucial for managing CNA.
  • Successful outcomes can be achieved with combined medical and surgical interventions.
  • This case contributes valuable data on CNA management in the Korean population.
Keywords:
AspergillosisDecorticationFungal infectionLung surgeryPleural disease

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