Related Experiment Video
Updated: May 24, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Effect of classroom air quality on students' concentration: results of a cluster-randomized cross-over experimental
D Twardella1, W Matzen, T Lahrz
1Department of Occupational and Environmental Health, Bavarian Health and Food Safety Authority, Munich, Germany. dorothee.twardella@lgl.bayern.de
Unlabelled:
To assess the effect of indoor air quality as indicated by the median carbon dioxide (CO₂) level in the classroom on the concentration performance (CP) of students, a cross-over cluster-randomized experimental study was conducted in 20 classrooms with mechanical ventilation systems. Test conditions 'worse' (median CO₂ level on average 2115 ppm) and 'better' (median CO₂ level on average 1045 ppm) were established by the regulation of the mechanical ventilation system on two days in one week each in every classroom. Concentration performance was quantified in students of grade three and four by the use of the d2-test and its primary parameter 'CP' and secondary parameters 'total number of characters processed' (TN) and 'total number of errors' (TE). 2366 d2-tests from 417 students could be used in analysis. In hierarchical linear regression accounting for repeated measurements, no significant effect of the experimental condition on CP or TN could be observed. However, TE was increased significantly by 1.65 (95% confidence interval 0.42-2.87) in 'worse' compared to 'better' condition. Thus, low air quality in classrooms as indicated by increased CO₂ levels does not reduce overall short-term CP in students, but appears to increase the error rate.
Practical Implications:
This study could not confirm that low air quality in classrooms as indicated by increased CO₂ levels reduces short-term concentration performance (CP) in students; however, it appears to affect processing accuracy negatively. To ensure a high level of accuracy, good air quality characterized, for example, by low CO₂ concentration should be maintained in classrooms.
More Related Videos
08:58Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
Published on: July 10, 2018
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
Related Concept Videos
Group Design
What is an Experiment?
Crossover Experiments
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs