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Updated: May 24, 2026

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Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
Lung transplantation for interstitial lung disease.
1Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Medical University of South Carolina, Charleston, SC 29425, USA. whelant@musc.edu
Clinics in Chest Medicine
|February 28, 2012
Summary
Lung transplantation is a viable option for patients with parenchymal lung disease unresponsive to medical treatment. This complex procedure offers improved survival and quality of life for carefully selected individuals.
Area of Science:
- Pulmonology
- Transplant Surgery
Background:
- Parenchymal lung disease can lead to progressive functional decline and increased mortality risk.
- Medical therapy may be insufficient for certain patients with advanced lung disease.
Purpose of the Study:
- To evaluate lung transplantation as a therapeutic option for selected patients with parenchymal lung disease.
Main Methods:
- This study reviews the indications and outcomes for lung transplantation in patients with parenchymal lung disease.
Main Results:
- Lung transplantation is a complex intervention requiring a dedicated multidisciplinary team.
- For carefully selected patients, lung transplantation offers a chance for increased survival and improved quality of life.
Conclusions:
- Lung transplantation is an appropriate therapeutic option for selected patients with parenchymal lung disease who have not responded to medical therapy.
