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Updated: May 24, 2026

In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA
Published on: May 21, 2015
[Dissertations 25 years after date 31. Black-pigmented oral bacteria in human oral infections]
1Uit de afdeling Orale Microbiologie, Centrum voor Tandheelkunde en Mondzorgkunde, Universitair Medisch Centrum Groningen. a.j.van.winkelhoff@med.umcg.nl
Abstract:
In 1986, oral microbiology, and especially the microbiology of periodontal infections, was of central importance. Interest in periodontology was growing rapidly and with it, interest in developments in microbiology and the immunology of infectious diseases of the periodontium. At national and international meetings discussions took place concerning the role of the newly discovered bacterial species Actinobacillus actinomycetemcomitans and the role of antibiotics in the treatment of severe periodontitis. Since the 1980s, much has changed in periodontology, not least of all as a result of a new specialism: oral implantology. With it, a new disease also came into existence: peri-implantitis.
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