Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Minimally invasive extraperitoneal posterior neurectomy for anterior cutaneous nerve entrapment syndrome (ACNES): Primary description of the MEPONE technique and clinical outcomes.

Hernia : the journal of hernias and abdominal wall surgery·2026
Same author

Additive and Multiplicative Effects of Socially Stigmatized Identities Using Linear Regression to Model Effects on Self-Reported Overall Health as Reported in the All of Us Research Program: Quantitative Analysis.

JMIR formative research·2026
Same author

Programmable Dual-Targeting Nano Bioconjugates: a Universal Bioconjugation Strategy to Enhance Single Molecule Proteomic Assays.

Small methods·2025
Same author

Adverse Reaction Reporting for Naxitamab in Chinese Expanded Access Treatment for Relapsed/Refractory High-Risk Neuroblastoma at the Children's Hospital of Fudan University.

Drugs - real world outcomes·2024
Same author

Robot-Assisted Extraperitoneal Ventral Hernia Repair-Experience From the First 160 Consecutive Operations With Lateral eTEP and eTAR Techniques.

Journal of abdominal wall surgery : JAWS·2024
Same author

Artificial Intelligence-What to Expect From Machine Learning and Deep Learning in Hernia Surgery.

Journal of abdominal wall surgery : JAWS·2024
Same journal

Machine Learning-Assisted Label-Free SERS Decoding of Mitochondrial Molecular Dynamics in Ovarian Granulosa Cells during Aging.

Analytical chemistry·2026
Same journal

Revealing the Regulatory Interplay of NHE1 mRNA and Na<sup>+</sup> in Cancer Cells Using a DNA Nanosensor.

Analytical chemistry·2026
Same journal

Towards Cellular Resolution of Tryptic Peptides in Tissue Sections by MALDI MS Imaging: A Focus on Enzyme Application and Reproducibility.

Analytical chemistry·2026
Same journal

Bioinspired Bilayer Hydrogel Colorimetric Sensor Array for Low-Temperature Food Freshness Analysis.

Analytical chemistry·2026
Same journal

Quartz Crystal Microbalance-Based Point-of-Care Testing Systems: Principles, Device Design, and Applications.

Analytical chemistry·2026
Same journal

Heterojunction Gate-Empowered OPECT Aptasensing: A Valid Protocol for Realizing High Current Gain at Low Electron Donor Dependency.

Analytical chemistry·2026
See all related articles

Related Experiment Video

Updated: May 24, 2026

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example
08:42

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Published on: October 26, 2016

A variable pressure method for characterizing nanoparticle surface charge using pore sensors.

Robert Vogel1, Will Anderson, James Eldridge

  • 1School of Mathematics and Physics, The University of Queensland, St. Lucia, QLD 4072, Australia. vogel@physics.uq.edu.au

Analytical Chemistry
|February 29, 2012
PubMed
Summary
This summary is machine-generated.

A new method uses resistive pulse sensors to measure nanoparticle electrokinetic surface charge by varying pressure. This technique accurately determines zeta potential, aligning with conductometric titration for surface charge analysis.

More Related Videos

Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

High Resolution Physical Characterization of Single Metallic Nanoparticles
09:56

High Resolution Physical Characterization of Single Metallic Nanoparticles

Published on: June 28, 2019

Related Experiment Videos

Last Updated: May 24, 2026

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example
08:42

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Published on: October 26, 2016

Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

High Resolution Physical Characterization of Single Metallic Nanoparticles
09:56

High Resolution Physical Characterization of Single Metallic Nanoparticles

Published on: June 28, 2019

Area of Science:

  • Nanotechnology
  • Surface Chemistry
  • Physical Chemistry

Background:

  • Accurate measurement of nanoparticle surface charge is crucial for understanding their behavior in various applications.
  • Existing methods like Phase Analysis Light Scattering (PALS) have limitations in certain scenarios.

Purpose of the Study:

  • To present a novel method for determining the electrokinetic surface charge of nanoparticles using resistive pulse sensing.
  • To validate the method's accuracy and compare it with established techniques.

Main Methods:

  • Utilized resistive pulse sensors to monitor nanoparticle blockade rates under varying applied pressures.
  • Applied pressure opposed electro-osmosis, electrophoresis, and inherent pressure to find an equilibrium point.
  • Calculated zeta potential from the applied pressure at the minimum blockade rate.

Main Results:

  • The variable pressure method successfully measured zeta potential for carboxylated polystyrene nanoparticles.
  • Results showed good agreement with Phase Analysis Light Scattering (PALS) measurements.
  • The sequence of increasing zeta potential correlated better with conductometric titration than PALS results.

Conclusions:

  • Resistive pulse sensing with variable pressure offers a viable alternative for electrokinetic surface charge measurements.
  • This method provides reliable zeta potential data that aligns with independent surface charge characterization techniques.