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[Lupus and protein deficiencies of the classical complement pathway]
L Weiss1, F Maillet, M Kazatchkine
1Unité d'immunopathologie et INSERM U28, hôpital Broussais, Paris.
La Revue Du Praticien
|September 21, 1990
Summary
Complement deficiencies, especially C4A, are common in systemic lupus erythematosus (SLE), increasing risks for autoimmune diseases and infections. Many SLE patients have the C4 AQO silent allele, linked to anti-SSA (Ro) antibodies.
Area of Science:
- Immunology
- Genetics
- Rheumatology