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Published on: May 6, 2018
Clinical significance of serum CA125 in nephrotic syndrome
1Department of Nephrology, Shandong University Qilu Hospital, Jinan, China. sesame_oil@126.com
Background:
To investigate the clinical significance of serum CA125 in the patients with nephrotic syndrome (NS).
Methods:
Three hundred and twenty-two patients with NS and 120 healthy volunteers were enrolled in our study. We measured serum CA125 and analyzed the probable relationship between elevated CA-125 levels in patients with NS, with and without ascites. Ascites were determined by B-mode ultrasonography in patients with NS.
Results:
Serum CA-125 in NS patients with ascites was significantly increased compared to NS patients without ascites (p < 0.05). There was no statistically significant difference between the healthy volunteers and the patients without ascites (p > 0.05).
Conclusions:
Serum CA125 is a useful index in the diagnosis of ultrasonographically detected ascites in patients with NS.
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