Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Visual System

Visual System

Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...

pV-Diagrams

pV-Diagrams

The pV diagram, which is a graph of pressure versus volume of the gas under study, is helpful in describing certain aspects of the substance. When the substance behaves like an ideal gas, the ideal gas equation describes the relationship between its pressure and volume. On a pV diagram, it is common to plot an isotherm, which is a curve showing p as a function of V with the number of molecules and the temperature fixed. Then, for an ideal gas, the product of the pressure of the gas and its...

Methods of Documentation V: CBE

Methods of Documentation V: CBE

Charting by Exception, or CBE, is a method of documentation used in healthcare, particularly in nursing, that focuses on documenting only significant or abnormal findings rather than recording every detail. This approach aims to streamline the documentation process, improve efficiency, and ensure that healthcare providers can quickly identify deviations from normalcy in patient assessments.
In CBE, healthcare professionals establish predefined standards of practice that define what constitutes...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cell-free recombinase-integrated Boolean output system.

Cell systems·2025

Same author

Constraint-Based Sub-Graph Partitioning for Multi-Cellular Biological Networks.

IEEE transactions on computational biology and bioinformatics·2025

Same author

Improving engineered biological systems with electronics and microfluidics.

Nature biotechnology·2025

Same author

Component library creation and pixel array generation with micromilled droplet microfluidics.

Microsystems & nanoengineering·2025

Same author

Integrated Real-Time CMOS Luminescence Sensing and Impedance Spectroscopy in Droplet Microfluidics.

IEEE transactions on biomedical circuits and systems·2024

Same author

Partitioning of a 2-bit hash function across 66 communicating cells.

Nature chemical biology·2024

Search research articles

Related Experiment Video

Updated: May 24, 2026

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Published on: November 24, 2021

DeviceEditor visual biological CAD canvas.

Joanna Chen¹, Douglas Densmore, Timothy S Ham

¹Fuels Synthesis Division, Joint BioEnergy Institute, Emeryville, CA 94608, USA. njhillson@lbl.gov.

Journal of Biological Engineering

|March 1, 2012

Summary

DeviceEditor is a web-based bioCAD software that simplifies synthetic biology design. It enables visual combinatorial library design and automates DNA assembly, saving researchers time and resources.

More Related Videos

In Silico Clinical Trials for Cardiovascular Disease

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

A Web Tool for Generating High Quality Machine-readable Biological Pathways

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Related Experiment Videos

Last Updated: May 24, 2026

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Interactive and Visualized Online Experimentation System for Engineering Education and Research

Published on: November 24, 2021

In Silico Clinical Trials for Cardiovascular Disease

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

A Web Tool for Generating High Quality Machine-readable Biological Pathways

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

Area of Science:

Synthetic Biology
Bioinformatics
Molecular Biology

Background:

Biological Computer Aided Design (bioCAD) is crucial for de novo design and selection of genetic components.
Synthetic Biology demands advanced bioCAD tools for combinatorial libraries, design rules, and DNA assembly.
Current bioCAD tools face challenges in meeting the complex needs of modern synthetic biology.

Purpose of the Study:

To develop and deploy a web-based bioCAD software, DeviceEditor.
To provide an intuitive graphical design environment for biological research.
To address the need for efficient combinatorial library design and DNA assembly automation.

Main Methods:

Development of DeviceEditor, a web-based bioCAD software.
Implementation of a graphical user interface mimicking laboratory whiteboarding.
Integration of visual combinatorial library design and scar-less DNA assembly automation.

Main Results:

DeviceEditor offers a visual design environment for biological constructs.
The software features direct integration for automated, scar-less multi-part DNA assembly.
Visualizations effectively display genetic component ordering and combinatorial variations.

Conclusions:

DeviceEditor empowers researchers by abstracting DNA manipulation, enabling prototype creation with standardized components.
Open interfaces facilitate integration with other bioCAD tools and platforms.
The software reduces costs and saves time through automated, reusable, and correct-by-construction design.