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Updated: May 24, 2026

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
Perioperative antibiotic in adenoidectomy with partial tonsillectomy: a randomized trial
Olaf Zagólski1, Jan Kulisiewicz
1ENT Department, St. John Grande's Hospital, Kraków, Poland. olafzag@gmail.com
Insights
Perioperative antibiotic therapy in children undergoing adenotonsillotomy significantly improved pain, recovery, and satisfaction. However, strict indications for antibiotics in this procedure are uncommon.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Pharmacology
Background:
- Adenotonsillotomy is a common procedure for pediatric obstructive sleep symptoms.
- The role of perioperative antibiotics in improving outcomes is debated.
Purpose of the Study:
- To evaluate the efficacy of perioperative antibiotic administration in pediatric adenotonsillotomy.
- To assess the impact on pain, recovery, and patient satisfaction.
Main Methods:
- A randomized controlled trial involving 120 children (aged 5-7 years) undergoing adenotonsillotomy.
- Participants received either intravenous and oral clindamycin or a placebo for seven days post-surgery.
Main Results:
- Significant improvements were observed in pain intensity and duration, return to normal activity, oral malodor, analgesic use, healing, and caregiver satisfaction in the antibiotic group.
- Only two patients in the placebo group showed indications for antibiotic treatment.
Conclusions:
- Perioperative antibiotics demonstrate significant benefits in the convalescence of children post-adenotonsillotomy.
- However, clear indications for antibiotic use in such cases are infrequent.
Objectives:
To examine potential benefits of perioperative antibiotic therapy in children undergoing adenotonsillotomy.
Methods:
Adenoidectomy with tonsillotomy was performed in 124 children with obstructive symptoms, aged 5-7 years. Of these, 120 completed the study. Intraoperative intravenous and postoperative oral clindamycin, or placebo for 7 days, were administered.
Results:
There were significant differences between the groups regarding pain intensity (p < 0.001) and duration (p < 0.05), day of return to normal physical activity (p < 0.05), occurrence and duration of oral malodor (p < 0.001), number of doses of additional analgesic (p < 0.001), healing grading (p < 0.05) and parents'/caregivers' satisfaction scores on the 4th postoperative day. There were indications for antibiotic in 2 individuals in the placebo group.
Conclusions:
There are significant differences in the course of convalescence related to perioperative antibiotic in children after adenotonsillotomy, but strict indications for antibiotics in these patients are rare.
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