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Updated: May 24, 2026

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A Murine Model of Subarachnoid Hemorrhage
Published on: November 21, 2013
Active bleeding in acute subarachnoid hemorrhage observed by multiphase dynamic-enhanced CT
1Department of Radiology, Tokyo Women’s Medical University Medical Center East, Tokyo, Japan. kasuzuki-rad@umin.ac.jp
AJNR. American Journal of Neuroradiology
|March 3, 2012
Summary
Active bleeding in acute subarachnoid hemorrhage (SAH) was detected in 25.5% of patients using multiphase dynamic-enhanced CT. This finding suggests active bleeding may influence SAH treatment strategies.
Area of Science:
- Neuroradiology
- Neurocritical Care
- Emergency Medicine
Background:
- Acute subarachnoid hemorrhage (SAH) is linked to aneurysm rebleeding.
- Advanced imaging now allows visualization of active bleeding in SAH.
Purpose of the Study:
- To investigate the incidence and characteristics of active bleeding in spontaneous SAH.
- To utilize multiphase dynamic-enhanced CT for detecting active bleeding.
Main Methods:
- Retrospective analysis of SAH patients undergoing 18-phase dynamic CT.
- Identification of contrast extravasation in source images.
- Comparison of clinical features between patients with and without extravasation.
Main Results:
- Active bleeding (contrast extravasation) detected in 25.5% of patients.
- Patients with extravasation had higher Claassen and WFNS grades and increased hematoma on follow-up CT.
- Extravasation was detected within 2 hours of SAH symptom onset.
Conclusions:
- Multiphase dynamic-enhanced CT reveals a significant incidence of active bleeding in acute SAH.
- Identifying active bleeding can potentially alter patient management and treatment strategies.
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