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Related Concept Videos

Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Imbalances in Cardiac Output01:26

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Updated: May 24, 2026

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
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Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Published on: December 2, 2014

Exercise-induced cardiac remodeling.

Rory B Weiner1, Aaron L Baggish

  • 1Cardiovascular Performance Program, Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA.

Progress in Cardiovascular Diseases
|March 6, 2012
PubMed
Summary
This summary is machine-generated.

Athletes often show cardiac enlargement due to vigorous exercise, a process called exercise-induced cardiac remodeling (EICR). This review covers the structural and functional heart changes observed in athletes.

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Related Experiment Videos

Last Updated: May 24, 2026

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
09:37

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Published on: December 2, 2014

A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats
07:31

A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats

Published on: December 2, 2016

Area of Science:

  • Cardiology
  • Sports Medicine
  • Physiology

Background:

  • Cardiac enlargement in athletes without disease has been noted since the late 1800s.
  • Repetitive vigorous exercise causes significant myocardial structural and functional changes.
  • Exercise-induced cardiac remodeling (EICR) is a recognized phenomenon in athletes.

Purpose of the Study:

  • To provide an overview of exercise-induced cardiac remodeling (EICR) in athletes.
  • To discuss the structural and functional cardiac alterations associated with intense physical activity.
  • To highlight the clinical relevance of EICR due to increased participation in athletics.

Main Methods:

  • Review of historical and contemporary scientific literature.
  • Analysis of documented cardiac changes in athletes.
  • Synthesis of findings on myocardial structure and function in response to exercise.

Main Results:

  • EICR involves left ventricular hypertrophy with sport-specific geometry (eccentric or concentric).
  • Systolic and diastolic functional alterations are recognized components of EICR.
  • These cardiac adaptations are common in individuals engaged in regular vigorous exercise.

Conclusions:

  • Exercise-induced cardiac remodeling is a well-documented adaptation in athletes.
  • Understanding EICR is crucial for differentiating physiological changes from pathology.
  • The prevalence of EICR necessitates awareness in clinical practice.