Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Asthma-IV: Nursing Management

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of the COVID-19 pandemic on adult asthma-related health care utilization.

The journal of allergy and clinical immunology. Global·2026

Same author

Guideline adherence to aeroallergen-focused activities in adult asthma care: Insights from an online survey.

The Journal of allergy and clinical immunology·2025

Same author

Impact of the COVID-19 Pandemic on Adult Asthma-Related Healthcare Utilization.

medRxiv : the preprint server for health sciences·2025

Same author

Recurrent Preschool Wheeze: The Impact of Adverse Social Drivers of Health and Opportunities for Interventions.

The journal of allergy and clinical immunology. In practice·2025

Same author

Maintenance of an Asthma Intervention Post-Trial: Use of a Patient-Activated Reliever-Triggered Inhaled Corticosteroid (PARTICS) Strategy in Black and Latinx Patients.

Journal of the American Board of Family Medicine : JABFM·2025

Same author

Augmenting electronic health record data with social and environmental determinant of health measures to understand regional factors associated with asthma exacerbations.

PLOS digital health·2025

Same journal

Tamoxifen-driven neutrophil reprogramming protects from pulmonary Granulibacter bethesdensis infection in chronic granulomatous disease.

The Journal of allergy and clinical immunology·2026

Same journal

Clinical and transcriptomic characterization of mixed granulocytic COPD phenotype.

The Journal of allergy and clinical immunology·2026

Same journal

Dupilumab outcomes in pediatric asthma by early eosinophil status: post hoc analysis of VOYAGE/EXCURSION.

The Journal of allergy and clinical immunology·2026

Same journal

Maternal antibiotic exposure alters the newborn metabolomic profile and increases the risk of respiratory infections in offspring: a 13-year longitudinal birth cohort study.

The Journal of allergy and clinical immunology·2026

Same journal

Selective Elimination of Mast Cells via Siglec-6-Targeted Nanodelivery of Drug Payload.

The Journal of allergy and clinical immunology·2026

Same journal

Loss of epidermal miR-149 sensitizes to skin inflammation.

The Journal of allergy and clinical immunology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 24, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Asthma outcomes: exacerbations.

Anne Fuhlbrigge¹, David Peden, Andrea J Apter

¹Brigham & Women's Hospital, Boston, MA, USA.

The Journal of Allergy and Clinical Immunology

|March 6, 2012

Summary

This summary is machine-generated.

Asthma exacerbation lacks a clear definition. Experts propose a standardized definition focusing on worsening asthma requiring systemic corticosteroids, with core outcomes for research.

More Related Videos

Methodology for Sputum Induction and Laboratory Processing

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

Related Experiment Videos

Last Updated: May 24, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Methodology for Sputum Induction and Laboratory Processing

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

Area of Science:

Pulmonary Medicine
Clinical Research Methodology
Asthma Management

Background:

Asthma treatment aims to prevent exacerbations, but lacks standardized terminology and severity assessment.
Current definitions of asthma exacerbations are inconsistent across studies.

Purpose of the Study:

To propose standardized asthma exacerbation outcomes for clinical research.
To establish a consensus on defining and assessing asthma exacerbations.

Main Methods:

Comprehensive literature reviews and expert opinion were utilized.
A workshop convened by the National Institutes of Health (NIH) discussed and finalized definitions.
Asthma exacerbation outcomes were classified as core, supplemental, or emerging.

Main Results:

No single dominant definition of asthma exacerbation was identified.
Commonly used definitions focused on treatment components: systemic corticosteroids, emergency visits/hospitalizations, and short-acting beta-agonist use.
Key components included systemic corticosteroid use, emergency department visits or hospitalizations, and quick-relief medication use.

Conclusions:

A proposed definition for asthma exacerbation is: 'a worsening of asthma requiring the use of systemic corticosteroids to prevent a serious outcome.'
Core outcomes for exacerbations should be included and reported separately in research.
A standardized, component-based definition with clear severity thresholds is recommended for future studies.