Recent trends in antibody based sensors

Area of Science:

• Biomedical Engineering
• Analytical Chemistry
• Immunotechnology

Background:

• Immunosensors and immunoassays are crucial for detecting antibody-antigen complexes.
• Technological advancements have expanded their applications and capabilities.
• A decade of progress has significantly impacted diagnostic and monitoring tools.

Purpose of the Study:

• To review recent advancements in immunosensor and immunoassay technologies over the past decade.
• To discuss emerging trends and future directions in the field.
• To highlight key improvements in sensor design and application.

Main Methods:

• Classification of immunosensors based on signal transduction mechanisms.
• Detailed discussion of electrochemical, optical, piezoelectric, and magnetic detection methods.
• Analysis of various applications, including continuous monitoring and point-of-care diagnostics.

Main Results:

• Significant progress in developing immunosensors for continuous analyte monitoring.
• Emergence of point-of-care (PoC) devices with reduced costs, enhanced automation, reusability, and ease of use.
• Diverse advancements in signal transduction and detection technologies.

Conclusions:

• Immunosensor technology has advanced rapidly, becoming a dynamic research area.
• Future trends point towards more integrated, automated, and accessible diagnostic solutions.
• The field shows great promise for revolutionizing medical diagnostics and health monitoring.