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Published on: February 1, 2012

Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease

Liping Zhou1, Huan Chen, Quan Wen

  • 1Department of Gastroenterology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

European Journal of Gastroenterology & Hepatology
|March 6, 2012
PubMed
Summary

Indoleamine 2,3-dioxygenase (IDO) is overexpressed in inflammatory bowel disease and may link innate and adaptive immunity. Steroids and salicylates reduce IDO expression, suggesting a potential therapeutic target for Crohn's disease and ulcerative colitis.

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