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Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.

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Related Experiment Video

Updated: May 24, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
09:37

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

The Bluejay genome browser.

Jung Soh1, Paul M K Gordon, Christoph W Sensen

  • 1Visual Genomics Centre, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

Current Protocols in Bioinformatics
|March 6, 2012
PubMed
Summary
This summary is machine-generated.

Bluejay is a Java-based genome browser for visualizing annotated genomes and genomic elements. It offers customizable displays, publication-quality graphics, and integrates gene expression data for comprehensive genomic analysis.

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Last Updated: May 24, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
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Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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10:40

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

Published on: December 22, 2017

Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Genomic data visualization is crucial for understanding complex biological information.
  • Existing tools may lack comprehensive features for multi-scale genome viewing and data integration.

Purpose of the Study:

  • To introduce Bluejay, a novel stand-alone genome browser.
  • To provide a versatile platform for multi-scale genomic data visualization and analysis.

Main Methods:

  • Developed Bluejay as a platform-independent, Java-based application.
  • Implemented features for customizable display, publication-quality graphics generation.
  • Integrated gene expression data visualization and multi-genome comparison capabilities.
  • Incorporated external, context-sensitive biological Web Services and waypoint navigation.

Main Results:

  • Bluejay enables multi-scale viewing of annotated genomes and genomic elements.
  • Users can customize display features and generate publication-quality graphics.
  • The tool facilitates interrelation of biological data, including gene expression and time-series data.
  • Supports concurrent comparison of multiple genomes and integration with external Web Services for in-depth analysis.

Conclusions:

  • Bluejay offers a comprehensive visual environment for studying genes in the context of their genome, transcriptome, and evolutionary origins.
  • The platform-independent and freely available nature of Bluejay promotes its accessibility and adoption in genomic research.