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Updated: May 24, 2026
An Analytical Tool-box for Comprehensive Biochemical, Structural and Transcriptome Evaluation of Oral Biofilms Mediated by Mutans Streptococci
Published on: January 25, 2011
[Study on the mechanism of erythritol effecting on Streptococcus mutans]
1Dept. of Pediatric Dentistry, Stomatology Hospital Affiliated to Fujian Medical University, Fuzhou 350002, China.
Objective:
To evaluate the effect of erythritol on cell wall structure of Streptococcus mutans (S. mutans) and explore its potential mechanism.
Methods:
Enzyme activities of lactate dehydrogenase (LDH) in bacterial solution were detected under respective condition of sucrose and erythritol. A scanning electron microscope (SEM) was used to investigate the change of S. mutans' cell wall under the condition of sucrose and erythritol.
Results:
Enzyme activities of LDH in erythritol culture medium were different from that in sucrose, but the difference was slight. SEM observation showed the integrity of cell wall was not destroyed and no content leaked out.
Conclusion:
It's suggested that erythritol has an antibacterial effect on S. mutans through no affecting on the normal structure of the cell wall of S. mutans.
