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Updated: May 24, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

Th17 cells induce a distinct graft rejection response that does not require IL-17A

E I Agorogiannis1, F S Regateiro, D Howie

  • 1University of Oxford, Sir William Dunn School of Pathology, South Parks Road, Oxford OX1 3RE, UK.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|March 7, 2012
PubMed
Summary

Tissue damage by helper T (Th17) cells in skin grafts does not require IL-17A. These cells caused epidermal hyperplasia and neutrophil infiltration, independent of IL-17A or interferon gamma neutralization.

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