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When a fetus survives methotrexate exposure

Tammy Donoway1, John Mandeville, Robert Gauer

  • 1Womack Army Medical Center, Fort Bragg, NC 28310, USA. tammy.donoway@us.army.mil

The Journal of Family Practice
|March 7, 2012
PubMed

Whether the drug is used for a medical abortion that ultimately fails or for other conditions when pregnancy is unsuspected, your counsel could be a patient's only resource.

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...