[Medical treatment of epulis by local injection penicillin therapy]

Treatment in November 1987, of an epulis-type gingival tumor, with in situ penicillin G injections, resulted in complete eradication of this benign tumor with no recurrence more than one year later. This case-report may be added to others of the same type reported by Dr. Joseph ABRAVANEL: since 1978, date of the first presentation at the "Hospital Necker Scientific Meeting", all cases treated (approximately ten) resulted in complete cure without any recurrence; the cases reported in 1978 were all followed and there was no recurrence. Since this technique demonstrated a superior efficacy over Surgery, we decided to report this last case with a follow-up period exceeding one year. However, we are aware, in spite of the long follow-up and the constant results, of the limited number of cases in the study. We hope that, with the help of all our colleagues, we will be able to improve our results. The mechanism of action of penicillin G opens a number of prospects in the pathology of the oral mucosa, especially iatrogenic pathologies: Cyclosporine, Dihydan, etc.